Dr. André P. Walther

Our lab uses techniques in Molecular Biology, Molecular Genetics, Biochemistry, Genomics, and Proteomics to understand how a protein called Replication Protein A (RPA) functions in DNA replication, Cell Cycle regulation, and DNA damage recognition and repair. We are using the Budding yeast, Saccharomyces cerevisiae as a model system to understand how RPA functions in humans.  This research will provide insights into the underlying causes of cancer, and other diseases caused by defects in chromosomal DNA maintenance.

I have also been entrusted with teaching Cell and Molecular Biology, Advanced Recombinant Techniques, an Advanced PCR techniques lab, a Cell Culture and Microscopy lab, and The Biology of Cancer. I also contribute to Principles of Biology, Ecology Evolution and Genetics, Junior Colloquium, and Molecular Genetics.


Michaela Ortiz '15 and Amanda Pattison '14 were each awarded an Undergraduate Research Grant from the Pennsylvania Academy of Science.

Amanda Pattison '14 had an Summer Undergraduate Research internship in the Department of Biochemistry at the University of Iowa College of Medicine.

Chelsea Mahoney '13 and
Amanda Pattison '14 gave poster presentations of their research at the 113th General Meeting of the American Society for Microbiology in Denver, CO.

Amanda Pattison '14 was awarded a 2012 American Society for Microbiology Undergraduate Research Fellowship to do summer research in the Walther lab.

Molly McQuilken '12  was accepted into the Molecular and Cellular Biology PhD program at Dartmouth College.

Kirsten Nole '12 had an internship at the Food Science Summer Scholars Program at Cornell University

Molly McQuilken '12  participated in the AMGEN Summer Scholars Program at University of Washington in Seattle.

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